Resolving inflammation, better than suppressing it?

Summary:
Inflammation is a crucial process in health and disease. Medical training has inflammation as a centrepiece, extolling the importance of molecules and processes which trigger and amplify the inflammatory response. Increasingly the interdependence of the nervous system and immune system have been accepted as scientific fact, allowing more coherent understanding of chronic pain and chronic inflammatory states. Medications have been targeted on increasingly subtle components of the inflammatory cascade, from prostaglandins, to cytokines.
However, why all this talk about starting inflammation? Nobody seems too verbal about what exactly resolves the normal inflammatory process?
Medicines to calm inflammation are typically crude and ineffective, dulling the entire body's response. It is becoming clear that nature has a sophisticated system for terminating inflammatory reactions. A set of key chemical mediators has been termed resolvins: fatty acid molecules derived from Omega 3 polyunsaturated fats. Fascinating research is uncovering how the solution to chronic pain and inflammation may not in fact be suppressing the inflammatory response, but making it resolve earlier.

Link:

Emerging roles of resolvins in the resolution of inflammation and pain

Key Points explored:
What are the properties of Resolvins in animal models of pain?
How do Resolvins mediate analgesia?
What are the links between pain and inflammation?

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