The Beginning - The Hallmarks of Cancer

Welcome to the Medical Student's Pertinent Reading List, wherein one can find accessible links to papers that fit following criteria:

• They provide a review of an area of study, rather than specifically investigating one theorem
• If they err on the side of having too much information, then it is all information that helps provide a basis for complete understanding of the subject at hand
• They are established papers that are up to date, but well recieved in peer review
• They are mostly on the subject of the scientific basis of medicine, albeit with a clinical leaning
• They are well written, and fascinating

Here is the paper that inspired the creation of the blog, "The Hallmarks of Cancer: The Next Generation" by Hanrahan et al. I hope you read it and find it as enjoyable as I did.

http://www.medicina1.uniroma1.it/UPLOADS/docs/690/the-hallmarks-of-cancer-the-next-generation.pdf

In summary, the paper establishes a few "hallmarks" that define the cellular behaviour of a malignancy. It does this with very neat diagrams, with a particularly good one showing the relationship between cellular behaviour and the macropatholoical processes that lead to metastasis.

I am open to suggestions of papers to post on here, just make sure they fit the criteria above. I think this endeavour works best as a blog rather than a wiki, because I want the papers to be very carefully regulated, unlike on wikis.

Enough from me, read the paper, and good learning!

Marblecake