Synthetic lethality - the hallmarks of chemo

McLornan et al obviously had me in mind when they wrote the review article,

Applying Synthetic Lethality for the Selective Targeting of Cancer

In the style of Hanrahan et al they break down the processes exploited in chemo into similar diagrams as in the Hallmarks of Cancer. Whilst none of this information is new, they present it in a very readable manner, framing neatly for easy understanding, and combining theory with examples of drugs using each mechanism discussed.

This makes an excellent primer for a medical student with an interest in oncology, or indeed any medical student who wants to read high quality papers. This blog was made for this kind of badass publication. Read it here. As yet I cannot find a free version of it so you might have to go through your local uni's wifi or something.